주메뉴 바로가기 컨텐츠 바로가기 하단 바로가기


 

연구실적

Home > 연구실적 > 국제학술논문지

 
작성일 : 15-01-16 16:51
연구단계 1단계 : 2년차
논문제목(영문) Clinical significance of chronic kidney disease and atrial fibrillation on morbidity and mortality in patients with acute myocardial infarction.
국내외구분 국외 SCI여부 SCI
연구책임자역활 교신저자 논문기여율 30%
주저자명 Hwang HS
교신저자명 Ahn Y
공동저자명 Park MW, Yoon HE, Chang YK, Yang CW, Kim SY, Cho JS, Kim CJ, Park GM, Park CS, Choi YS, Koh YS, Lee JM, Shin DI, Seo SM, Jeon DS, Moon KW, Yoo KD, Kim HY, Kim DB, Park HJ, Kim PJ, Chang K, Chung WS, Seung KB, Jeong MH, Her SH
게제년월일 2014-10-29
ISSN 0250-8095
Impact Factor 2.646
학술지명 Am J Nephrol
서지사항 0집 / 40권 / 4호,   페이지(345 - 352)
병기표기 3개
Acknowledgement
기재여부

※ Acknowledgement가 기재된 논문만 연구과제의 성과로 인정.
- 국문 표기 : "본 연구는 보건복지부 보건의료연구개발사업의 지원에 의하여 이루어진 것임. (HI13C1527)"
- 영문 표기 : "This study was supported by a grant of the Korean Health Technology R&D Project,
(HI13C1527) Ministry of Health & Welfare, Republic of Korea. "
요약초록문
(Abstract) 입력
BACKGROUND/AIMS: Atrial fibrillation (AF) often coexists with acute myocardial infarction (AMI), and chronic kidney disease (CKD) is a major risk for AMI. However, the combined impact of CKD and AF on the mortality and morbidity in AMI population has not been determined.
METHODS: Between January 2004 and December 2009, a total of 4,738 AMI patients were enrolled prospectively. Patients were divided into four groups according to the combined status of CKD and AF. The primary endpoint was a combination of 5-year major adverse cardiac and cerebrovascular events (MACCE).
RESULTS: The prevalence of AF was significantly higher in CKD patients than in non-CKD patients (6.76 vs. 3.31%, p < 0.001). The highest cumulative event rate of MACCE and death was observed in patients with both CKD and AF (68.5 and 64.0%), respectively. In multivariable analyses, compared with patients with neither AF nor CKD, hazard ratios (HR) for composite of MACCE were 1.66 (95% CI, 1.14-2.41), 1.24 (95% CI, 1.06-1.46), and 2.10 (95% CI, 1.42-3.13) for patients with AF only, those with CKD only, and those with both CKD and AF, respectively (p for interaction = 0.935). Patients with both CKD and AF had a greatest risk for all-cause mortality (HR 2.54; 95% CI, 1.60-4.53), and the significant synergistic interaction was observed between CKD and AF (p for interaction = 0.015).
CONCLUSION: The combined effect of AF and CKD on the risk of MACCE after an AMI is stronger than any separate condition, and it confers a synergistic effect on the all-cause mortality risk.

 
Total 26
번호 논문제목 저자 교신저자 학술지명
26 Comparison of the effects of two low-density lipop… Cho KH Jeong MH Int J Cardiol
25 Impact of renal function on changes of plaque char… Hong YJ Jeong MH Int J Cardiol
24 Reliable femoral chronic total occlusion model usi… Kim NY, Lim KS Jeong MH J Mater Sci Mater Med
23 Cardioprotective effect of fimasartan, a new Angio… Sim DS Jeong MH J Korean Med SCI
22 Clinical significance of chronic kidney disease an… Hwang HS Ahn Y Am J Nephrol
21 Impact of postdischarge statin withdrawal on long-… Kim MC Ahn Y Am J Cardiol
20 Impact of low level of high-density lipoprotein-ch… JI MS Jeong MH J Cardiol
19 In vivo evaluation and characterization of a bio-a… Park SA Jeong MH, Park JK Materials Letters
18 Comparison of second-generation drug-eluting versu… Piao ZH Jeong MH Int J Cardiol
17 Current Trend of Acute Myocardial Infarction in Ko… Kook HY Jeong MH Am J Cardiol
16 Gallic acid inhibits vascular calcification throug… Kee HJ Jeong MH Vascul Pharmacol
15 Sulforaphane suppresses cardiac hypertrophy by inh… Kee HJ Jeong MH Mol Nutr Food Res
14 QRS morphology and ventricular dyssynchrony in pat… Lee KH Cho JG Int J Cardiol
13 Structural, optical, and selective ethanol sensing… C. Balamurugan Lee DW Sensor Actuat B-Chem
12 Fabrication of biomimetic PCL scaffold using rapid… SA Park SA Park Macromol Res
 1  2