작성일 : 15-01-30 12:38
| 연구단계 | 1단계 : 2년차 | ||
| 논문제목(영문) | Comparing High-Intensity Versus Low-to Moderate-Intensity Statin Therapy in Korean Patients with Acute Myocardial Infarction | ||
| 국내외구분 | 국내 | SCI여부 | SCI(E) |
| 연구책임자역활 | 교신저자 | 논문기여율 | 30% |
| 주저자명 | Kim M, Kim HK | ||
| 교신저자명 | Ahn Y | ||
| 공동저자명 | Park HK, Jeong MH, Cho JG, Park JC, Kim YJ, Cho MC, Kim CJ | ||
| 게제년월일 | 2014-12-26 | ||
| ISSN | 2287-2892 | ||
| Impact Factor | 0 | ||
| 학술지명 | J Lipid Atheroscler | ||
| 서지사항 | 0집 / 3권 / 2호, 페이지(85 - 92) | ||
| 병기표기 | 2개 | ||
| Acknowledgement 기재여부 |
예
※ Acknowledgement가 기재된 논문만 연구과제의 성과로 인정. - 국문 표기 : "본 연구는 보건복지부 보건의료연구개발사업의 지원에 의하여 이루어진 것임. (HI13C1527)" - 영문 표기 : "This study was supported by a grant of the Korean Health Technology R&D Project, (HI13C1527) Ministry of Health & Welfare, Republic of Korea. " |
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| 요약초록문 (Abstract) 입력 |
Objective: The aim of this study is to compare the clinical benefits between high-intensity and low-to moderate-intensity statin therapy in patients with acute myocardial infarction (AMI). Methods: A total of 1,230 patients in the Korea AMI Registry (KAMIR) were enrolled. Patients were divided into two groups according to the dosage of statin for the secondary prevention after AMI. The primary endpoint was composite of major adverse cardiac events (MACEs) including cardiac death, non-fatal MI, repeat revascularization during the 12 months of clinical follow-up. Result: The primary endpoint occurred in 101 patients (11.3%) from the low-to moderate-intensity statin group and 45 patients (13.4%) from the high-intensity statin group. The cumulative incidence of MACEs during 12-month follow-up was not significantly different between the two groups (p=0.323). After multi-variate analysis, MACEs-free survival rate was not significantly different between the two groups. Conclusion: High-intensity statin therapy did not show additional clinical benefit over low-to moderate-intensity statin therapy after AMI. |
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