연구단계 | 1단계 : 2년차 | ||
논문제목(영문) | Impact of Smoking on Clinical Outcomes in Female Patients with Acute Myocardial Infarction | ||
국내외구분 | 국내 | SCI여부 | SCI(E) |
연구책임자역활 | 교신저자 | 논문기여율 | 30% |
주저자명 | Jeong YA | ||
교신저자명 | Jeong MH | ||
공동저자명 | Jeong HC, Ahn Y, Kim YJ, Kim CJ, Cho MC | ||
게제년월일 | 2015-01-01 | ||
ISSN | 1738-5520 | ||
Impact Factor | 0.986 | ||
학술지명 | Korean Circ J | ||
서지사항 | 0집 / 45권 / 1호, 페이지(22 - 27) | ||
병기표기 | 1개 | ||
Acknowledgement 기재여부 |
예
※ Acknowledgement가 기재된 논문만 연구과제의 성과로 인정. - 국문 표기 : "본 연구는 보건복지부 보건의료연구개발사업의 지원에 의하여 이루어진 것임. (HI13C1527)" - 영문 표기 : "This study was supported by a grant of the Korean Health Technology R&D Project, (HI13C1527) Ministry of Health & Welfare, Republic of Korea. " |
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요약초록문 (Abstract) 입력 |
Background and Objectives: Cigarette smoking has been recognized as a prominent threat to women’s health. We investigated the impact of smoking on clinical outcomes in Korean female patients after acute myocardial infarction (AMI). Subjects and Methods: Out of the AMI patients who enrolled in the Korea AMI Registry, 4444 female patients were included in this study. Patients were divided into two groups–non-smoker and smoker–according to their current smoking status. We compared in-hospital mortality and major adverse cardiac events (MACE), including cardiac death, myocardial infarction, repeated percutaneous coronary intervention (PCI), or coronary artery bypass grafting during the one-year clinical follow-up period between two groups. Results: The non-smoker group had more hypertension (HTN) and diabetes mellitus. The levels of total cholesterol, triglyceride, and lowdensity lipoprotein cholesterol were higher in the non-smoker group. However, in-hospital mortality was significantly higher in the smoker group (1.0% vs. 2.4%, p=0.002), and cardiac death during the 12-month clinical follow-up was significantly more frequent in the smoker group (2.2% vs. 4.5%, p=0.003). Total MACEs during the 12 months were higher in the smoker group (4.9% vs. 6.8%, p=0.014). Smoking and HTN were independent predictors of MACE {odds ratio (OR): 1.742, 95% confidence interval (CI): 1.010–3.000, p=0.046; OR: 1.573, 95% CI: 1.003–2.466, p=0.049, respectively}. Conclusion: Female smokers with AMI showed significantly higher in-hospital mortality and MACE rates during the one-year clinical follow-up period. |
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